Scripps Staff Scientist 

Ph.D. and/or MD in an appropriate scientific discipline required. A minimum of 2 years postdoctoral experience.

A Staff Scientist position is available in the Ron Davis Lab at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation &Technology in Jupiter, Florida. The work will focus on drug discovery for neurodegenerative diseases as related primarily to mitochondrial biology and the mitochondrial dysfunction that occurs in neurodegenerative diseases. ALS is the primary disease focus. The potential projects within this area include but are not limited to:

• Cell based assays (primarily imaging) for mitochondrial biology using human, normal and diseased iPSC-derived neurons.
• Cell based assays (primarily imaging) for mitochondrial biology as related to other interacting organelles, including the endoplasmic reticulum, lysosomes, and the nucleus.
• High throughput assay development to measure various parameters of mitochondrial function.
• Testing novel compounds for their ability to offset the mitochondrial dysfunction that occurs in neurodegenerative diseases and iPSC-derived neurons representative of the disease.
• Testing promising compounds for their in vivo pharmacokinetic properties in wildtype and mouse models for neurodegenerative diseases.
• Testing promising compounds for efficacy using mouse models for neurodegenerative diseases.
• Identifying targets and mechanism of action for novel compounds that have been identified.

The laboratory environment is collaborative, employing a wide variety of approaches and techniques used in modern drug discovery and neuroscience. The Wertheim UF Scripps Institute provides an outstanding intellectual environment and access to a wide range of cutting-edge technologies. Please visit laboratory website at https://scripps.ufl.edu/profile/davis-ronald-1/ for more details.

Commensurate with experience.  

Must have postdoctoral experience in Chemistry or the Biological Sciences.

• Demonstrated expertise in at least one of the project areas listed above, or expertise in a related area that would directly translate into expertise in the listed project areas.
• Excellent communication skills, both oral and written.
• Ability to vigorously move a project forward with little day-to-day supervision.
• Ability to work in a team environment with other lab members.

In order to be considered, you must upload your cover letter and resume.

Please provide names and email addresses of three to five references as part of the application process. When ready, the hiring department will contact the listed references via email requesting their reference letters to be uploaded directly to the application website.

This position is open until filled. Application review will begin June 19, 2025. 

This position is time-limited.