Scientific Laboratory Manager

Apply now Job no: 537471
Work type: Staff Full-Time
Location: Orange
Categories: Biology/Life Science, Grant or Research Administration, Health Care Administration/Support
Department:29052001 - MD-INST FOR THERAPEUTIC INNOV

Classification Title:

Scientific Laboratory Manager

Classification Minimum Requirements:

Bachelor’s degree in an appropriate area and two years of relevant experience. Appropriate college course work may substitute at an equivalent rate for the required experience.

Job Description:

The Department of Medicine, Institute of Therapeutic Innovation is seeking a full time Scientific Laboratory Manager. This position will organize and direct the daily activities of the laboratory. The manager will be responsible for supervising laboratory personnel, conducting and overseeing quality assurance and quality control, and collecting, analyzing, and interpreting lab results.  The manager will use technical problem solving skills to perform standardized or repetitive testing in the BSL2 and BSL3 microbiology laboratory of the UF Institute for Therapeutic Innovation in Orlando, FL. This position will be responsible for conducting novel experiments using Pharmacokinetic / Pharmacodynamic principles to develop antimicrobial drug regimens that optimize the treatment of infections. The employee will follow all federal, state and local regulations pertaining to assigned laboratory and animal facilities and will be registered with the USDA and US Dept. HHS for access to high consequence biological agents. Work practices will follow strict biosafety and biosecurity protocols. The individual must obtain and maintain all required security and suitability clearances. Due to federal regulation, the position is open to US citizens only. Offer contingent on a successful pre-employment screening which includes a review of criminal records, reference checks, and verification of education.

Essential Functions;

Laboratory Management:
• Oversees operational aspects of BSL-3 and ABSL-2/3 laboratories.
• Ensures compliance with federal regulations for regulated biological materials.
• Researches and evaluates new products, compares and negotiates vendor prices.
• Develop laboratory procedures.
• Assists in development of operating budgets.
• Coordinates the developmental and maintenance the safety program for all laboratory settings.
• Instruct staff in quality control and analytical procedures.
• Monitor performance of quality control systems to ensure effectiveness and efficiency.
• Instruct staff in quality control and analytical procedures.
• Review statistical studies, technological advances, or regulatory standards and trends to stay abreast of issues in the field of quality control.
• Categorizes and stores sensitive scientific materials/instruments.

Laboratory and husbandry functions:
Participate in therapeutic experiments using antibiotics or other compounds and be available for variable therapeutic dosing schedules. Perform all work with viable select biological agents in a BSL-3 biocontainment suite(s). This effort may require vaccinations and use of personal protective equipment, as appropriate. Assist with and performs work including, but not limited to, the following:
• Perform laboratory tests/experiments in the BSL-2 and BSL-3 laboratories following established procedures or protocols without deviations unless approved by laboratory manager or supervisor. Conduct studies using Good Laboratory Practices (GLP) and assist with generation of standard operating procedures and reports that meet these standards.
• Harvest, purification and storage of bacterial cells and spores.
• Prepare sterile solutions for use in microbial assays. Prepare solutions and reagents following standard laboratory procedures. Use of a spectrophotometer and ultracentrifugation.
• Determination of the viability and purity of suspensions of infectious agents.
• Performance of ELISA and toxin neutralization assays on sera from animals.
• Prepare, clean, and sterilize glassware and instruments, general laboratory housekeeping and animal husbandry. Solve laboratory equipment and experimentation set up problems.
• Assist in design and preparation of all models, including animal, minimum inhibitory concentration and hollow fiber infection studies. Will include but not limited to inoculations and drug therapy procedures.
• Be able to perform administration of bacteria and therapeutics via nasal passages, sub cutaneous injections, intra peritoneal injections, intramuscular injections and oral gavage technics. Assist in training on techniques in BSL2 and BSL3 including but not limited to animal necropsies, tissue processing and inactivation protocols
• Monitor inventory levels, count/record orders upon receipt and maintain accountability records.
• Performance of cell labeling and cell sorting experiments.
• Preparation of DNA/RNA, PCR and analysis of samples.
• The use of computer for ordering supplies, and processing, analyzing, and storing data will be required.
• Specific projects may utilize GLP requirements/documentation.
• Animal husbandry duties and general cleaning. 
• Autoclaving, waste removal and general cleaning duties required.
• Present data at weekly meeting.
• Be willing to accept additional roles and responsibilities as required.
• Meet schedules and deadlines as set by supervisory personnel.

Compliance: Assist with compliance of all requirements mandated by the inspecting entities including but not limited to IACUC and BSL2/3 safety inspections and federal inspections to continue and maintain operational status. 
• Weekly
• Monthly
• Bi-Annual
• Annual
Assist with maintaining regulatory records of laboratory operations.
Responsible for preparing laboratory and vivarium for inspections and audits through daily common practices.
Responsible for maintaining an operational and safety environment.
Required annual Trainings that include manual, SOP and Protocol reviews.
Required to keep inventory records and data management in compliance
Including but not limited to animal husbandry duties
Keep Laboratory Manager well informed of any issues in the laboratory including practices, equipment, training, supplies, and records.
Shipping and transportation training and requirements
Export Control Training

General Supervision and Management:
This position will require consistent communication with the Principal investigators for projects oversite and communication the ITI BSL3 Manager for the general oversite and functioning of the laboratory. Provide general supervision to laboratory staff. Provides input into process development/improvement based on observations made in the laboratory and literature reviews. Assist with ordering and managing of inventory of supplies and ordering common use supplies. Assist with validation and verification processes within the ITI BSL3. Will assist in supervision and training of use for the multiple inventories of the Heine Laboratory. Assist in making arrangements for maintenance of laboratory and experimental equipment to be decontaminated form the BSL3 laboratory. Assist with gathering, organizing, verifying and validating data for generating manuscripts and reports. Assist with coordination of CO2 tanks and Laundry deliveries, etc. Assist with coordination project schedules for on call and afterhours staff. Must have the flexibility to work as a backup that requires to be positioned within 20 minutes of the building of on-call schedules. Coordinate training for new staff and new procedures. Will require minimal travel to the Main campus on average once a year. Travel as needed for conferences. Must be will to perform general cleaning of the laboratories and oversee the staff of properly cleaning also. Manage and maintain the cleaning rosters for multiple areas associated with the laboratory.  Confirm staff or performing environmental sampling as required.  Assist with supervision for vendors as needed.

Expected Salary:

$70,000 - $92,200 Annually

Required Qualifications:

Bachelor’s degree in an appropriate area and two years of relevant experience. Appropriate college course work may substitute at an equivalent rate for the required experience.

Preferred:

Other preferred qualifications include 3 years of experience in a BSL3 containment supervisor, ALAAS certification, animal husbandry in an ABSL2/3 and BSL2 experience. Experience with mentorship practice in BSL3 work environment specifically.  Experience working with vertebrate animals in a laboratory research setting and organizational skills and ability to pay close attention to details are essential.  Histopathological training and certification required.

Special Instructions to Applicants:

In order to be considered, you must upload your resume.

Application must be submitted by 11:55 p.m. (ET) of the posting end date.

Health Assessment Required: Yes

 

Advertised: Eastern Daylight Time
Applications close: Eastern Daylight Time

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